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Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Beta cell loss in Type 1 and Type 2 diabetes mellitus may result from apoptosis and necrosis induced by inflammatory mediators. The suppressor of cytokine signalling (SOCS)-3 is a natural inhibitor of cytokine signalling and also influences insulin signalling. SOCS3 could therefore be a candidate gene in the development of Type 1 and Type 2 diabetes mellitus.
OriginalsprogEngelsk
TidsskriftDiabetologia
Vol/bind47
Udgave nummer7
Sider (fra-til)1273-7
Antal sider5
ISSN0012-186X
DOI
StatusUdgivet - 1 jul. 2004

ID: 33902590