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Normal overall leakiness of microvasculature for albumin in patients with chronic obstructive lung disease (COLD)

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Standard

Normal overall leakiness of microvasculature for albumin in patients with chronic obstructive lung disease (COLD). / Kok-Jensen, A; Henriksen, Jens Henrik Sahl.

I: Scandinavian Journal of Clinical & Laboratory Investigation, Bind 44, Nr. 2, 1984, s. 119-23.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Kok-Jensen, A & Henriksen, JHS 1984, 'Normal overall leakiness of microvasculature for albumin in patients with chronic obstructive lung disease (COLD)', Scandinavian Journal of Clinical & Laboratory Investigation, bind 44, nr. 2, s. 119-23.

APA

Kok-Jensen, A., & Henriksen, J. H. S. (1984). Normal overall leakiness of microvasculature for albumin in patients with chronic obstructive lung disease (COLD). Scandinavian Journal of Clinical & Laboratory Investigation, 44(2), 119-23.

Vancouver

Kok-Jensen A, Henriksen JHS. Normal overall leakiness of microvasculature for albumin in patients with chronic obstructive lung disease (COLD). Scandinavian Journal of Clinical & Laboratory Investigation. 1984;44(2):119-23.

Author

Kok-Jensen, A ; Henriksen, Jens Henrik Sahl. / Normal overall leakiness of microvasculature for albumin in patients with chronic obstructive lung disease (COLD). I: Scandinavian Journal of Clinical & Laboratory Investigation. 1984 ; Bind 44, Nr. 2. s. 119-23.

Bibtex

@article{523311204b8b11df928f000ea68e967b,
title = "Normal overall leakiness of microvasculature for albumin in patients with chronic obstructive lung disease (COLD)",
abstract = "The overall extravasation rate of albumin, TER (i.e. the fraction of the intravascular albumin mass (IVM) passing into, and during steady state returning from, the extravascular space per unit time) was determined from the disappearance of i.v. injected radioiodinated serum albumin in seven patients with severe chronic obstructive lung disease (COLD) and in seven normal controls. Arterial oxygen tension in patients with COLD was median 60 mmHg (range 47-80, normal greater than 75 mmHg), vital capacity was on the average 55{\%} of expected normal value (median 1.80 litre, range 1.45-1.95), and forced expired volume in first sec was decreased to 21{\%} of expected normal value (median 0.55 litre, range 0.40-0.70). Right-heart catheterization revealed pulmonary hypertension in all but one patient. TER in patients with COLD was median 6.1{\%} IVM/h (range 3.5-10.1) as compared to that of normal controls 6.0{\%} IVM/h (range 4.3-7.4), indicating that no significant change in microvascular leakiness to albumin could be found in patients with COLD. Thus, the results bring no support to a generally increased microvascular permeability to proteins in patients with COLD.",
author = "A Kok-Jensen and Henriksen, {Jens Henrik Sahl}",
note = "Keywords: Aged; Blood Volume; Capillary Permeability; Female; Heart Catheterization; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Serum Albumin; Spirometry",
year = "1984",
language = "English",
volume = "44",
pages = "119--23",
journal = "Scandinavian Journal of Clinical & Laboratory Investigation",
issn = "0036-5513",
publisher = "Taylor & Francis",
number = "2",

}

RIS

TY - JOUR

T1 - Normal overall leakiness of microvasculature for albumin in patients with chronic obstructive lung disease (COLD)

AU - Kok-Jensen, A

AU - Henriksen, Jens Henrik Sahl

N1 - Keywords: Aged; Blood Volume; Capillary Permeability; Female; Heart Catheterization; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Serum Albumin; Spirometry

PY - 1984

Y1 - 1984

N2 - The overall extravasation rate of albumin, TER (i.e. the fraction of the intravascular albumin mass (IVM) passing into, and during steady state returning from, the extravascular space per unit time) was determined from the disappearance of i.v. injected radioiodinated serum albumin in seven patients with severe chronic obstructive lung disease (COLD) and in seven normal controls. Arterial oxygen tension in patients with COLD was median 60 mmHg (range 47-80, normal greater than 75 mmHg), vital capacity was on the average 55% of expected normal value (median 1.80 litre, range 1.45-1.95), and forced expired volume in first sec was decreased to 21% of expected normal value (median 0.55 litre, range 0.40-0.70). Right-heart catheterization revealed pulmonary hypertension in all but one patient. TER in patients with COLD was median 6.1% IVM/h (range 3.5-10.1) as compared to that of normal controls 6.0% IVM/h (range 4.3-7.4), indicating that no significant change in microvascular leakiness to albumin could be found in patients with COLD. Thus, the results bring no support to a generally increased microvascular permeability to proteins in patients with COLD.

AB - The overall extravasation rate of albumin, TER (i.e. the fraction of the intravascular albumin mass (IVM) passing into, and during steady state returning from, the extravascular space per unit time) was determined from the disappearance of i.v. injected radioiodinated serum albumin in seven patients with severe chronic obstructive lung disease (COLD) and in seven normal controls. Arterial oxygen tension in patients with COLD was median 60 mmHg (range 47-80, normal greater than 75 mmHg), vital capacity was on the average 55% of expected normal value (median 1.80 litre, range 1.45-1.95), and forced expired volume in first sec was decreased to 21% of expected normal value (median 0.55 litre, range 0.40-0.70). Right-heart catheterization revealed pulmonary hypertension in all but one patient. TER in patients with COLD was median 6.1% IVM/h (range 3.5-10.1) as compared to that of normal controls 6.0% IVM/h (range 4.3-7.4), indicating that no significant change in microvascular leakiness to albumin could be found in patients with COLD. Thus, the results bring no support to a generally increased microvascular permeability to proteins in patients with COLD.

M3 - Journal article

C2 - 6719017

VL - 44

SP - 119

EP - 123

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

SN - 0036-5513

IS - 2

ER -

ID: 19345078