Forskning ved Københavns Universitet - Københavns Universitet

Forside

Novel Targets for Treatment of Pseudomonas aeruginosa Biofilms

Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiFormidling

Pseudomonas aeruginosa causes infection in all parts of the human body. The bacterium is naturally resistant to a wide range of antibiotics. In addition to resistance mechanisms such as efflux pumps, the ability to form aggregates, known as biofilm, further reduces Pseudomonas aeruginosa’s susceptibility to antibiotics. The presence of such biofilms is acknowledged to equal a persistent infection due to their inherent high tolerance to all antimicrobials and immune cells. In this chapter we discuss the mechanisms of biofilm tolerance. The latest biofilm research is reviewed and future treatment strategies such as quorum sensing inhibitors, silver, and antibodies are thoroughly evaluated.
OriginalsprogEngelsk
TitelAntibiofilm Agents
RedaktørerKendra Rumbaugh
Antal sider16
Vol/bind8
ForlagSpringer Publishing Company
Publikationsdato1 jan. 2014
Sider257-272
ISBN (Trykt) 978-3-642-53832-2
ISBN (Elektronisk)978-3-642-53833-9
StatusUdgivet - 1 jan. 2014
NavnSpringer Series on Biofilms
Vol/bind8

ID: 112933602