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N-terminal pro-B-type natriuretic peptide in patients with growth hormone disturbances

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Acromegaly is associated with hypertrophic cardiomyopathy, hypertension and subsequent congestive heart failure. Impairment of cardiac function has also been associated with growth hormone deficiency (GHD). B-type natriuretic peptides (BNPs) have emerged as strong diagnostic and prognostic risk markers. They are cardioprotective hormones that compensate heart disease by promoting natriuresis and modulation of cardiac hypertrophy in response to volume expansion and ventricular wall stretch.
OriginalsprogEngelsk
TidsskriftClinical Endocrinology
Vol/bind66
Udgave nummer5
Sider (fra-til)619-25
Antal sider7
ISSN0300-0664
DOI
StatusUdgivet - maj 2007

ID: 92190531