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Østrogen til forebyggelse af recidiverende urinvejsinfektioner hos postmenopausale kvinder--gennemgang af et Cochrane-review

Publikation: Bidrag til tidsskriftTidsskriftartikel

Recurrent urinary tract infections (UTIs) are common in postmenopausal women. While the pathophysiology is often complex, it is evident that the urogenital atrophy due to the decrease of endogenous oestrogen production is a key factor. Two small randomized controlled studies have proven the efficacy of local (vaginal) oestrogen therapy in the prevention of recurrent UTIs. Conversely, four randomized trials, reviewed in a weighted meta-analysis with pooled data from 2,798 women, have shown the lack of efficacy of systemic oestrogen-progesterone therapy. Local oestrogen therapy is recommended, if the predominant indication is urogenital symptoms.
Udgivelsesdato: 2009-Aug
OriginalsprogDansk
TidsskriftUgeskrift for læger
Vol/bind171
Udgave nummer36
Sider (fra-til)2568-71
Antal sider4
ISSN0041-5782
StatusUdgivet - 2009

ID: 20568584