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Optimizing peroperative compliance with PEEP during upper abdominal surgery: Effects on perioperative oxygenation and complications in patients without preoperative cardiopulmonary dysfunction

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Optimizing peroperative compliance with PEEP during upper abdominal surgery : Effects on perioperative oxygenation and complications in patients without preoperative cardiopulmonary dysfunction. / Wetterslev, J.; Hansen, E. G.; Roikjaer, O.; Kanstrup, I. L.; Heslet, L.

I: European Journal of Anaesthesiology, Bind 18, Nr. 6, 01.12.2001, s. 358-365.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Wetterslev, J, Hansen, EG, Roikjaer, O, Kanstrup, IL & Heslet, L 2001, 'Optimizing peroperative compliance with PEEP during upper abdominal surgery: Effects on perioperative oxygenation and complications in patients without preoperative cardiopulmonary dysfunction', European Journal of Anaesthesiology, bind 18, nr. 6, s. 358-365. https://doi.org/10.1046/j.0265-0215.2000.00842.x

APA

Wetterslev, J., Hansen, E. G., Roikjaer, O., Kanstrup, I. L., & Heslet, L. (2001). Optimizing peroperative compliance with PEEP during upper abdominal surgery: Effects on perioperative oxygenation and complications in patients without preoperative cardiopulmonary dysfunction. European Journal of Anaesthesiology, 18(6), 358-365. https://doi.org/10.1046/j.0265-0215.2000.00842.x

Vancouver

Wetterslev J, Hansen EG, Roikjaer O, Kanstrup IL, Heslet L. Optimizing peroperative compliance with PEEP during upper abdominal surgery: Effects on perioperative oxygenation and complications in patients without preoperative cardiopulmonary dysfunction. European Journal of Anaesthesiology. 2001 dec 1;18(6):358-365. https://doi.org/10.1046/j.0265-0215.2000.00842.x

Author

Wetterslev, J. ; Hansen, E. G. ; Roikjaer, O. ; Kanstrup, I. L. ; Heslet, L. / Optimizing peroperative compliance with PEEP during upper abdominal surgery : Effects on perioperative oxygenation and complications in patients without preoperative cardiopulmonary dysfunction. I: European Journal of Anaesthesiology. 2001 ; Bind 18, Nr. 6. s. 358-365.

Bibtex

@article{60e85df44f14483e958a3e0a417c43f3,
title = "Optimizing peroperative compliance with PEEP during upper abdominal surgery: Effects on perioperative oxygenation and complications in patients without preoperative cardiopulmonary dysfunction",
abstract = "Background and objective: Late postoperative hypoxaemia after upper abdominal surgery is common even among cardiopulmonary healthy patients. Atelectasis may develop after intubation and persist into or reveal a disposition for atelectasis in the postoperative period. Positive end-expiratory pressure (PEEP) eliminates peroperative atelectasis but the effect on perioperative oxygenation is controversial. This study evaluated the effect of peroperative PEEP optimized pulmonary compliance on perioperative oxygenation and complications. Methods: Forty patients assessed by electrocardiography, spirometry, functional residual capacity and diffusion capacity were randomly assigned to receive positive end-expiratory pressure (PEEP) or zero end-expiratory pressure (ZEEP) during surgery. PaO2, SPO2 and complications in the postoperative period were evaluated without knowledge of peroperative PEEP or ZEEP application. Results: Peroperative arterial oxygenation improved for all patients receiving PEEP, mean 2.1 kPa (0.7-3.5 kPa). There was no difference in postoperative median PaO2 between the groups. The differences in the incidence of late prolonged postoperative hypoxaemia and complications were 25{\%} (-5{\%} to 55{\%}) and -1{\%} (-31{\%} to 29{\%}) between the ZEEP and the PEEP group, but were not statistically significant.",
keywords = "Anaesthesia General, Anaesthesia Inhalation, isoflurane, Anaesthesia, epidural, Anaesthetics, Local, bupivacaine, Anoxaemia, Atelectasis, Pneumonia, Positive-Pressure Respiration, Postoperative Complications",
author = "J. Wetterslev and Hansen, {E. G.} and O. Roikjaer and Kanstrup, {I. L.} and L. Heslet",
year = "2001",
month = "12",
day = "1",
doi = "10.1046/j.0265-0215.2000.00842.x",
language = "English",
volume = "18",
pages = "358--365",
journal = "European Journal of Anaesthesiology. Supplement",
issn = "0952-1941",
publisher = "Lippincott Williams & Wilkins, Ltd.",
number = "6",

}

RIS

TY - JOUR

T1 - Optimizing peroperative compliance with PEEP during upper abdominal surgery

T2 - Effects on perioperative oxygenation and complications in patients without preoperative cardiopulmonary dysfunction

AU - Wetterslev, J.

AU - Hansen, E. G.

AU - Roikjaer, O.

AU - Kanstrup, I. L.

AU - Heslet, L.

PY - 2001/12/1

Y1 - 2001/12/1

N2 - Background and objective: Late postoperative hypoxaemia after upper abdominal surgery is common even among cardiopulmonary healthy patients. Atelectasis may develop after intubation and persist into or reveal a disposition for atelectasis in the postoperative period. Positive end-expiratory pressure (PEEP) eliminates peroperative atelectasis but the effect on perioperative oxygenation is controversial. This study evaluated the effect of peroperative PEEP optimized pulmonary compliance on perioperative oxygenation and complications. Methods: Forty patients assessed by electrocardiography, spirometry, functional residual capacity and diffusion capacity were randomly assigned to receive positive end-expiratory pressure (PEEP) or zero end-expiratory pressure (ZEEP) during surgery. PaO2, SPO2 and complications in the postoperative period were evaluated without knowledge of peroperative PEEP or ZEEP application. Results: Peroperative arterial oxygenation improved for all patients receiving PEEP, mean 2.1 kPa (0.7-3.5 kPa). There was no difference in postoperative median PaO2 between the groups. The differences in the incidence of late prolonged postoperative hypoxaemia and complications were 25% (-5% to 55%) and -1% (-31% to 29%) between the ZEEP and the PEEP group, but were not statistically significant.

AB - Background and objective: Late postoperative hypoxaemia after upper abdominal surgery is common even among cardiopulmonary healthy patients. Atelectasis may develop after intubation and persist into or reveal a disposition for atelectasis in the postoperative period. Positive end-expiratory pressure (PEEP) eliminates peroperative atelectasis but the effect on perioperative oxygenation is controversial. This study evaluated the effect of peroperative PEEP optimized pulmonary compliance on perioperative oxygenation and complications. Methods: Forty patients assessed by electrocardiography, spirometry, functional residual capacity and diffusion capacity were randomly assigned to receive positive end-expiratory pressure (PEEP) or zero end-expiratory pressure (ZEEP) during surgery. PaO2, SPO2 and complications in the postoperative period were evaluated without knowledge of peroperative PEEP or ZEEP application. Results: Peroperative arterial oxygenation improved for all patients receiving PEEP, mean 2.1 kPa (0.7-3.5 kPa). There was no difference in postoperative median PaO2 between the groups. The differences in the incidence of late prolonged postoperative hypoxaemia and complications were 25% (-5% to 55%) and -1% (-31% to 29%) between the ZEEP and the PEEP group, but were not statistically significant.

KW - Anaesthesia General, Anaesthesia Inhalation, isoflurane

KW - Anaesthesia, epidural

KW - Anaesthetics, Local, bupivacaine

KW - Anoxaemia

KW - Atelectasis

KW - Pneumonia

KW - Positive-Pressure Respiration

KW - Postoperative Complications

UR - http://www.scopus.com/inward/record.url?scp=0035740787&partnerID=8YFLogxK

U2 - 10.1046/j.0265-0215.2000.00842.x

DO - 10.1046/j.0265-0215.2000.00842.x

M3 - Journal article

C2 - 11412288

AN - SCOPUS:0035740787

VL - 18

SP - 358

EP - 365

JO - European Journal of Anaesthesiology. Supplement

JF - European Journal of Anaesthesiology. Supplement

SN - 0952-1941

IS - 6

ER -

ID: 203890611