Forskning ved Københavns Universitet - Københavns Universitet


Padma-28, et urtepraeparat, øger gangdistancen hos patienter med claudicatio intermittens

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Thirty-six patients with stable intermittent claudication were randomized in a doubleblind study either to treatment with two tablets of Padma-28 twice daily (containing 340 mg dried herbal mixture composed according to an ancient lamaistic prescription) or placebo for four months. Effect of treatment was quantified by measurements of systemic and peripheral systolic blood pressures, and pain-free and maximal walking distances on a tread-mill. The actively treated group attained a significant increase in pain-free walking distance from 115 m (72-218) to 227 m (73- >1000, p <0.05). The placebo group did not show significant changes in either pain-free or maximal walking distance. Significant changes in systemic or peripheral blood pressures could not be demonstrated in any of the groups. In conclusion, our study has shown that treatment with Padma-28 over a four month period significantly increases the walking distance in patients with stable intermittent claudication of long duration.
TidsskriftUgeskrift for Laeger
Udgave nummer42
Sider (fra-til)6207-9
Antal sider3
StatusUdgivet - 17 okt. 1994

ID: 34073762