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Parathyroideahormonrelateret peptid-induceret humoral hyperkalkæmi ved malignitet

Publikation: Bidrag til tidsskriftReview

Humoral hypercalcaemia of malignancy (HHM) is defined by a tumor producing hypercalcemia through a systemic hormone or cytokine. In approximately 80% of HHM cases, parathyroid hormone-related peptide (PTHrP) is the causal factor. Primary hyperparathyroidism (PHPT) and metastasis to the bone are the most important differential diagnoses. The treatment strategy in cases of HHM is to decrease the serum calcium by fluid, loop diuretics, glucorticoids and bisphosphonate. Moreover, the underlying malignant disease should be treated. The prognosis for patients with HHM, however, is poor.

OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind167
Udgave nummer8
Sider (fra-til)924-926
Antal sider3
ISSN0041-5782
StatusUdgivet - 21 feb. 2005

ID: 203876739