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Permeability and ultrastructure of human bladder epithelium

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Leakage of tight junctions as observed with electron microscopy and demonstration of solute transport across bladder epithelium was investigated in 13 patients with different bladder diseases: urinary retention and infection, bladder tumours and interstitial cystitis. The latter group showed consistent leakage of solutes through the urothelium. Electron microscopy revealed leaky tight junctions. This finding might be helpful in establishing the histological criteria and explain the pathogenesis of interstitial cystitis.
OriginalsprogEngelsk
TidsskriftBritish Journal of Urology
Vol/bind55
Udgave nummer5
Sider (fra-til)488-92
Antal sider5
ISSN0007-1331
StatusUdgivet - okt. 1983

ID: 47629792