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Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Alvar Agustí
  • Lisa D Edwards
  • Stephen I Rennard
  • William MacNee
  • Ruth Tal-Singer
  • Bruce E Miller
  • Jørgen Vestbo
  • David A Lomas
  • Peter M A Calverley
  • Emiel Wouters
  • Courtney Crim
  • Julie C Yates
  • Edwin K Silverman
  • Harvey O Coxson
  • Per Bakke
  • Ruth J Mayer
  • Bartolome Celli
  • Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators
Because chronic obstructive pulmonary disease (COPD) is a heterogeneous condition, the identification of specific clinical phenotypes is key to developing more effective therapies. To explore if the persistence of systemic inflammation is associated with poor clinical outcomes in COPD we assessed patients recruited to the well-characterized ECLIPSE cohort (NCT00292552).
OriginalsprogEngelsk
TidsskriftP L o S One
Vol/bind7
Udgave nummer5
Sider (fra-til)e37483
ISSN1932-6203
DOI
StatusUdgivet - 2012

ID: 48599117