Forskning ved Københavns Universitet - Københavns Universitet

Forside

Pharmacological consequences of long-term morphine treatment in patients with cancer and chronic non-malignant pain

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

In patients with pain of malignant origin morphine may be administered in high and often increasing doses during extended periods of time. In patients with chronic pain of non-malignant origin morphine may be an important remedy, and in these cases the goal is to keep the morphine dose stable. The pharmacokinetic as well as the pharmacodynamic consequences of long-term morphine treatment with special reference to the two most important metabolites of morphine morphine-6-glucuronide (M-6-G) and morphine-3-glucuronide (M-3-G) remain to be settled.
OriginalsprogEngelsk
TidsskriftEuropean Journal of Pain
Vol/bind8
Udgave nummer3
Sider (fra-til)263-71
Antal sider9
ISSN1090-3801
DOI
StatusUdgivet - jun. 2004

ID: 46098448