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Plasmid segregation: spatial awareness at the molecular level

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Jakob Moller-Jensen
  • Kenn Gerdes
In bacteria, low- copy number plasmids ensure their stable inheritance by partition loci ( par), which actively distribute plasmid replicates to each side of the cell division plane. Using time- lapse. fluorescence microscopic tracking of segregating plasmid molecules, a new study provides novel insight into the workings of the par system from Escherichia coli plasmid R1. Despite its relative simplicity, the plasmid partition spindle shares characteristics with the mitotic machinery of eukaryotic cells.
OriginalsprogEngelsk
TidsskriftJournal of Cell Biology
Vol/bind179
Udgave nummer5
Sider (fra-til)813-815
Antal sider3
ISSN0021-9525
DOI
StatusUdgivet - 2007
Eksternt udgivetJa

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