Forskning ved Københavns Universitet - Københavns Universitet


Prevalence and Clinico–Pathological Features of Peste des Petits Ruminants in Different Breeds of Goats and their Response to Antimicrobial

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Kamrul Islam
  • Abdul Ahad
  • A. Mahmood
  • M.M. Rahman
  • Islam, Md Zohorul
  • M.H.B. Kabir
  • M. Barua
  • Sharmin Chowdhury
  • M.K. Nasir
  • P.K. Biswas
Peste des petits ruminant (PPR) is an acute febrile viral disease of small ruminants characterized by mucopurulent nasal and ocular discharges, necrotizing and erosive stomatitis, enteritis and pneumonia. Present study was carried out on one hundred and eighty two goats during July to December, 2012. Black Bengal goats depicted higher prevalence (P = 0.66) than Crossbred and Jamunapari goats. Clinical examination revealed significantly increased heart (P = 0.00), temperature (P = 0.00) and respiratory rates (P = 0.00) in PPR affected goats (n = 87) than healthy goats (P < 0.05). Significantly higher prevalence (P < 0.00) of PPR (65%) was recorded in non vaccinated group (n = 102, P < 0.05) whereas non-significant difference in PPR was recorded with respect to breed (P = 0.66), sex (P = 0.68) and month (P = 0.50) of disease occurrence (P > 0.05). Blood samples of PPR affected goats (n = 10) exhibited significantly decreased (P = 0.02) total leukocyte count (9.31±0.53 thousand/mm3) and (P = 0.01) lymphocytes (41.20±2.26%) (P < 0.05), whereas significantly increased (P = 0.02) neutrophils (41.30±2.32%) as compared to healthy goats (n = 10) (P < 0.05). Postmortem examination of PPR suspected goats revealed characteristics zebra stripe lesions at ileo–caecal junction. The study suggests that PPR can affect goat population irrespective of age, breed and sex. Supportive therapy with Oxytetracycline can enhance recovery of the PPR affected goats and vaccination can reduce the disease prevalence leading to effective control and prevention.
TidsskriftJournal of Infection and Molecular Biology
Udgave nummer3
Sider (fra-til)43-48
Antal sider6
StatusUdgivet - 2014
Eksternt udgivetJa

ID: 137343581