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Projected Lifetime Healthcare Costs Associated with HIV Infection

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Fumiyo Nakagawa
  • Alec Miners
  • Colette J Smith
  • Ruth Simmons
  • Rebecca K Lodwick
  • Valentina Cambiano
  • Lundgren, Jens
  • Valerie Delpech
  • Andrew N Phillips
Objective

Estimates of healthcare costs associated with HIV infection would provide valuable insight for evaluating the cost-effectiveness of possible prevention interventions. We evaluate the additional lifetime healthcare cost incurred due to living with HIV.

Methods

We used a stochastic computer simulation model to project the distribution of lifetime outcomes and costs of men-who-have-sex-with-men (MSM) infected with HIV in 2013 aged 30, over 10,000 simulations. We assumed a resource-rich setting with no loss to follow-up, and that standards and costs of healthcare management remain as now.

Results

Based on a median (interquartile range) life expectancy of 71.5 (45.0–81.5) years for MSM in such a setting, the estimated mean lifetime cost of treating one person was £360,800 ($567,000 or €480,000). With 3.5% discounting, it was £185,200 ($291,000 or €246,000). The largest proportion (68%) of these costs was attributed to antiretroviral drugs. If patented drugs are replaced by generic versions (at 20% cost of patented prices), estimated mean lifetime costs reduced to £179,000 ($281,000 or €238,000) and £101,200 ($158,900 or €134,600) discounted.

Conclusions

If 3,000 MSM had been infected in 2013, then future lifetime costs relating to HIV care is likely to be in excess of £1 billion. It is imperative for investment into prevention programmes to be continued or scaled-up in settings with good access to HIV care services. Costs would be reduced considerably with use of generic antiretroviral drugs.
OriginalsprogEngelsk
Artikelnummere0125018
TidsskriftPloS one
Sider (fra-til)1-12
Antal sider12
ISSN1932-6203
DOI
StatusUdgivet - 2015

ID: 159107309