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Prolapse reduction deteriorates the urethral closure mechanism

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Prolapse reduction deteriorates the urethral closure mechanism. / Khayyami, Yasmine; Lose, Gunnar; Klarskov, Niels.

I: International Urogynecology Journal, Bind 30, Nr. 3, 2019, s. 489-493.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Khayyami, Y, Lose, G & Klarskov, N 2019, 'Prolapse reduction deteriorates the urethral closure mechanism', International Urogynecology Journal, bind 30, nr. 3, s. 489-493. https://doi.org/10.1007/s00192-018-3647-x

APA

Khayyami, Y., Lose, G., & Klarskov, N. (2019). Prolapse reduction deteriorates the urethral closure mechanism. International Urogynecology Journal, 30(3), 489-493. https://doi.org/10.1007/s00192-018-3647-x

Vancouver

Khayyami Y, Lose G, Klarskov N. Prolapse reduction deteriorates the urethral closure mechanism. International Urogynecology Journal. 2019;30(3):489-493. https://doi.org/10.1007/s00192-018-3647-x

Author

Khayyami, Yasmine ; Lose, Gunnar ; Klarskov, Niels. / Prolapse reduction deteriorates the urethral closure mechanism. I: International Urogynecology Journal. 2019 ; Bind 30, Nr. 3. s. 489-493.

Bibtex

@article{54e698acc7d447eea9ac2d8002e8eba8,
title = "Prolapse reduction deteriorates the urethral closure mechanism",
abstract = "INTRODUCTION AND HYPOTHESIS: Pelvic organ prolapse (POP) reduction is often performed in the preoperative assessment of women before POP surgery. Using urethral pressure reflectometry (UPR), we sought to investigate how POP reduction affects the urethral closure mechanism.METHODS: Women with anterior or posterior vaginal wall prolapse stage ≥II with and without POP reduction were examined with a speculum. We performed prolapse staging according to the Pelvic Organ Prolapse Quantification system, UPR measurements at rest and during squeezing, and standardized stress tests with 300 ml saline. All examinations were repeated after insertion of a speculum.RESULTS: We included 38 women: 22 with anterior and 16 with posterior vaginal wall prolapse POP-Q stage  ≥II. During POP reduction, resting and squeezing urethral pressures decreased by 2.5 cmH2O (p = 0.007) and 5.1 cmH2O (p < 0.0001), respectively, in all women. During POP reduction, the number of positive stress tests increased from four (18%) to eight (36%) in women with anterior vaginal wall prolapse and from one (6%) to nine (56%) in women with posterior vaginal wall prolapse.CONCLUSIONS: POP reduction decreases urethral pressure, especially during squeezing, and consequently increases the number of positive stress tests. The test itself artificially deteriorates the urethral closure mechanism.",
keywords = "Female, Gynecological Examination, Humans, Middle Aged, Pelvic Organ Prolapse/complications, Pressure, Urethra/physiopathology, Urinary Incontinence, Stress/etiology, Urodynamics",
author = "Yasmine Khayyami and Gunnar Lose and Niels Klarskov",
year = "2019",
doi = "10.1007/s00192-018-3647-x",
language = "English",
volume = "30",
pages = "489--493",
journal = "International Urogynecology Journal",
issn = "0937-3462",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - Prolapse reduction deteriorates the urethral closure mechanism

AU - Khayyami, Yasmine

AU - Lose, Gunnar

AU - Klarskov, Niels

PY - 2019

Y1 - 2019

N2 - INTRODUCTION AND HYPOTHESIS: Pelvic organ prolapse (POP) reduction is often performed in the preoperative assessment of women before POP surgery. Using urethral pressure reflectometry (UPR), we sought to investigate how POP reduction affects the urethral closure mechanism.METHODS: Women with anterior or posterior vaginal wall prolapse stage ≥II with and without POP reduction were examined with a speculum. We performed prolapse staging according to the Pelvic Organ Prolapse Quantification system, UPR measurements at rest and during squeezing, and standardized stress tests with 300 ml saline. All examinations were repeated after insertion of a speculum.RESULTS: We included 38 women: 22 with anterior and 16 with posterior vaginal wall prolapse POP-Q stage  ≥II. During POP reduction, resting and squeezing urethral pressures decreased by 2.5 cmH2O (p = 0.007) and 5.1 cmH2O (p < 0.0001), respectively, in all women. During POP reduction, the number of positive stress tests increased from four (18%) to eight (36%) in women with anterior vaginal wall prolapse and from one (6%) to nine (56%) in women with posterior vaginal wall prolapse.CONCLUSIONS: POP reduction decreases urethral pressure, especially during squeezing, and consequently increases the number of positive stress tests. The test itself artificially deteriorates the urethral closure mechanism.

AB - INTRODUCTION AND HYPOTHESIS: Pelvic organ prolapse (POP) reduction is often performed in the preoperative assessment of women before POP surgery. Using urethral pressure reflectometry (UPR), we sought to investigate how POP reduction affects the urethral closure mechanism.METHODS: Women with anterior or posterior vaginal wall prolapse stage ≥II with and without POP reduction were examined with a speculum. We performed prolapse staging according to the Pelvic Organ Prolapse Quantification system, UPR measurements at rest and during squeezing, and standardized stress tests with 300 ml saline. All examinations were repeated after insertion of a speculum.RESULTS: We included 38 women: 22 with anterior and 16 with posterior vaginal wall prolapse POP-Q stage  ≥II. During POP reduction, resting and squeezing urethral pressures decreased by 2.5 cmH2O (p = 0.007) and 5.1 cmH2O (p < 0.0001), respectively, in all women. During POP reduction, the number of positive stress tests increased from four (18%) to eight (36%) in women with anterior vaginal wall prolapse and from one (6%) to nine (56%) in women with posterior vaginal wall prolapse.CONCLUSIONS: POP reduction decreases urethral pressure, especially during squeezing, and consequently increases the number of positive stress tests. The test itself artificially deteriorates the urethral closure mechanism.

KW - Female

KW - Gynecological Examination

KW - Humans

KW - Middle Aged

KW - Pelvic Organ Prolapse/complications

KW - Pressure

KW - Urethra/physiopathology

KW - Urinary Incontinence, Stress/etiology

KW - Urodynamics

U2 - 10.1007/s00192-018-3647-x

DO - 10.1007/s00192-018-3647-x

M3 - Journal article

C2 - 29644382

VL - 30

SP - 489

EP - 493

JO - International Urogynecology Journal

JF - International Urogynecology Journal

SN - 0937-3462

IS - 3

ER -

ID: 241643730