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Reduceret cerebralt stofskifte korrelerer med MRI-forandringer og kognitiv dysfunktion hos patienter med dissemineret sklerose

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Magnetic resonance imaging (MRI) lesion load is widely used in the clinical evaluation of patients with multiple sclerosis (MS), but little is known about the associated changes in cortical activation. For this purpose, we studied the association between the corticocerebral metabolic rate of glucose (CMRglc) and the MRI T2-weighted total lesion area (TLA). In addition, we investigated the correlation between cognitive and neurological disability and CMRglc.
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind163
Udgave nummer27
Sider (fra-til)3788-92
Antal sider5
ISSN0041-5782
StatusUdgivet - 2 jul. 2001

Bibliografisk note

Reduced metabolism in cerebral cortex correlates with MRI changes and cognitive dysfunction in patients with disseminated sclerosis

    Forskningsområder

  • Adult, Aged, Cerebral Cortex, Cognition Disorders, Deoxyglucose, Evoked Potentials, Motor, Female, Glucose, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Multiple Sclerosis, Neuropsychological Tests, Tomography, Emission-Computed

ID: 32640193