Forskning ved Københavns Universitet - Københavns Universitet

Forside

Regional cerebral blood flow during rest and skilled hand movements by Xenon-133 inhalation and emission computerized tomography

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Regional cerebral blood flow (CBF) was studied in 16 normal adult volunteers during rest and in 10 the study was repeated during skilled hand movements. A fast-rotating ('dynamic'), single-photon emission computerized tomograph (ECT) with four detector heads was used. Xenon-133 was inhaled over a 1-min period at a concentration of 10 mCi/L. The arrival and washout of the radioisotope was recorded during four 1-min periods. Two slices, 2 cm thick, 7 and 12 cm above the orbitomeatal line were obtained in every study. CBF averaged 60 ml/100/g/min (SD ± 11) in the lower slice and 51 ml/100/g/min (SD ± 13) in the upper slice. A symmetric pattern comparing right to left sides was found in both slices. Finger tapping and writing with the right hand increased CBF in specific areas of the upper slice: in the contralateral hand area by 35 ± 15% (p<0.025), and in the supplementary motor area on both sides by 34 ± 15% (p<0.025).

OriginalsprogEngelsk
TidsskriftJournal of Cerebral Blood Flow and Metabolism
Vol/bind1
Udgave nummer4
Sider (fra-til)385-389
Antal sider5
ISSN0271-678X
DOI
StatusUdgivet - 1 jan. 1981

ID: 201460565