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Regional glucose phosphorylation rate in rat brain during acute ethanol intoxication.

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Standard

Regional glucose phosphorylation rate in rat brain during acute ethanol intoxication. / Brøndsted, H E; Reith, J; Gjedde, A.

I: Acta Neurologica Scandinavica, Bind 81, Nr. 3, 1990, s. 229-32.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Brøndsted, HE, Reith, J & Gjedde, A 1990, 'Regional glucose phosphorylation rate in rat brain during acute ethanol intoxication.', Acta Neurologica Scandinavica, bind 81, nr. 3, s. 229-32.

APA

Brøndsted, H. E., Reith, J., & Gjedde, A. (1990). Regional glucose phosphorylation rate in rat brain during acute ethanol intoxication. Acta Neurologica Scandinavica, 81(3), 229-32.

Vancouver

Brøndsted HE, Reith J, Gjedde A. Regional glucose phosphorylation rate in rat brain during acute ethanol intoxication. Acta Neurologica Scandinavica. 1990;81(3):229-32.

Author

Brøndsted, H E ; Reith, J ; Gjedde, A. / Regional glucose phosphorylation rate in rat brain during acute ethanol intoxication. I: Acta Neurologica Scandinavica. 1990 ; Bind 81, Nr. 3. s. 229-32.

Bibtex

@article{0740dcb0b31511debc73000ea68e967b,
title = "Regional glucose phosphorylation rate in rat brain during acute ethanol intoxication.",
abstract = "The effect of ethanol on regional cerebral metabolic rate for glucose (rCMRglc) was studied in rats using [6-14C]glucose. After intravenous injection, radioactivity was determined in 14 brain regions, corrected for loss of label, and divided by the integral of the arterial plasma glucose concentration measured during tracer circulation. When blood ethanol concentration was maintained at 6 g/l by intravenous infusion of ethanol for approximately 1 h, rCMRglc was found to be reduced significantly in 7 forebrain regions, compared to values of conscious control animals. In 7 further regions including brain stem regions, rCMRglc was not significantly reduced. We conclude that the effects of severe acute alcohol intoxication resemble those of global anesthesia.",
author = "Br{\o}ndsted, {H E} and J Reith and A Gjedde",
year = "1990",
language = "English",
volume = "81",
pages = "229--32",
journal = "Acta Neurologica Scandinavica",
issn = "0001-6314",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - Regional glucose phosphorylation rate in rat brain during acute ethanol intoxication.

AU - Brøndsted, H E

AU - Reith, J

AU - Gjedde, A

PY - 1990

Y1 - 1990

N2 - The effect of ethanol on regional cerebral metabolic rate for glucose (rCMRglc) was studied in rats using [6-14C]glucose. After intravenous injection, radioactivity was determined in 14 brain regions, corrected for loss of label, and divided by the integral of the arterial plasma glucose concentration measured during tracer circulation. When blood ethanol concentration was maintained at 6 g/l by intravenous infusion of ethanol for approximately 1 h, rCMRglc was found to be reduced significantly in 7 forebrain regions, compared to values of conscious control animals. In 7 further regions including brain stem regions, rCMRglc was not significantly reduced. We conclude that the effects of severe acute alcohol intoxication resemble those of global anesthesia.

AB - The effect of ethanol on regional cerebral metabolic rate for glucose (rCMRglc) was studied in rats using [6-14C]glucose. After intravenous injection, radioactivity was determined in 14 brain regions, corrected for loss of label, and divided by the integral of the arterial plasma glucose concentration measured during tracer circulation. When blood ethanol concentration was maintained at 6 g/l by intravenous infusion of ethanol for approximately 1 h, rCMRglc was found to be reduced significantly in 7 forebrain regions, compared to values of conscious control animals. In 7 further regions including brain stem regions, rCMRglc was not significantly reduced. We conclude that the effects of severe acute alcohol intoxication resemble those of global anesthesia.

M3 - Journal article

C2 - 2353572

VL - 81

SP - 229

EP - 232

JO - Acta Neurologica Scandinavica

JF - Acta Neurologica Scandinavica

SN - 0001-6314

IS - 3

ER -

ID: 14943578