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Regulation of regional cerebral blood flow during and between migraine attacks

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Standard

Regulation of regional cerebral blood flow during and between migraine attacks. / Lauritzen, Martin; Olsen, Tom Skyhoj; Lassen, Niels A.; Paulson, Olaf B.

I: Annals of Neurology, Bind 14, Nr. 5, 01.01.1983, s. 569-572.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Lauritzen, M, Olsen, TS, Lassen, NA & Paulson, OB 1983, 'Regulation of regional cerebral blood flow during and between migraine attacks', Annals of Neurology, bind 14, nr. 5, s. 569-572. https://doi.org/10.1002/ana.410140512

APA

Lauritzen, M., Olsen, T. S., Lassen, N. A., & Paulson, O. B. (1983). Regulation of regional cerebral blood flow during and between migraine attacks. Annals of Neurology, 14(5), 569-572. https://doi.org/10.1002/ana.410140512

Vancouver

Lauritzen M, Olsen TS, Lassen NA, Paulson OB. Regulation of regional cerebral blood flow during and between migraine attacks. Annals of Neurology. 1983 jan 1;14(5):569-572. https://doi.org/10.1002/ana.410140512

Author

Lauritzen, Martin ; Olsen, Tom Skyhoj ; Lassen, Niels A. ; Paulson, Olaf B. / Regulation of regional cerebral blood flow during and between migraine attacks. I: Annals of Neurology. 1983 ; Bind 14, Nr. 5. s. 569-572.

Bibtex

@article{4b9d303e52894be8b49844787e9dd38b,
title = "Regulation of regional cerebral blood flow during and between migraine attacks",
abstract = "Cerebrovascular reactivity to voluntary hyperventilation, moderate hypertension, and physiological activation was studied in nine patients during induced migraine attacks and in four patients between their attacks. Regional cerebral blood flow was measured by the xenon 133 injection technique in 254 areas of one hemisphere. The partly hypoperfused hemisphere allowed for comparison of adjacent hypoperfused and normally perfused brain areas. During attacks the carbon dioxide reactivity was decreased to 2.8 ± 0.8{\%} per mm Hg in the oligemic regions compared with 5.8 ± 0.8{\%} per mm Hg in the normally perfused brain. Blood pressure autoregulation was normal in all brain regions. Regional blood flow increase in response to physiological activation was severely impaired in the hypoperfused brain areas, whereas neighboring normally perfused regions reacted normally. Confinement of the regulation abnormalities to the area of the oligemia supports our suggestion that the blood flow changes are caused by a change in local metabolism. Between attacks of migraine, the patients had normal regulation of brain circulation.",
author = "Martin Lauritzen and Olsen, {Tom Skyhoj} and Lassen, {Niels A.} and Paulson, {Olaf B.}",
year = "1983",
month = "1",
day = "1",
doi = "10.1002/ana.410140512",
language = "English",
volume = "14",
pages = "569--572",
journal = "Annals of Neurology",
issn = "0364-5134",
publisher = "JohnWiley & Sons, Inc.",
number = "5",

}

RIS

TY - JOUR

T1 - Regulation of regional cerebral blood flow during and between migraine attacks

AU - Lauritzen, Martin

AU - Olsen, Tom Skyhoj

AU - Lassen, Niels A.

AU - Paulson, Olaf B.

PY - 1983/1/1

Y1 - 1983/1/1

N2 - Cerebrovascular reactivity to voluntary hyperventilation, moderate hypertension, and physiological activation was studied in nine patients during induced migraine attacks and in four patients between their attacks. Regional cerebral blood flow was measured by the xenon 133 injection technique in 254 areas of one hemisphere. The partly hypoperfused hemisphere allowed for comparison of adjacent hypoperfused and normally perfused brain areas. During attacks the carbon dioxide reactivity was decreased to 2.8 ± 0.8% per mm Hg in the oligemic regions compared with 5.8 ± 0.8% per mm Hg in the normally perfused brain. Blood pressure autoregulation was normal in all brain regions. Regional blood flow increase in response to physiological activation was severely impaired in the hypoperfused brain areas, whereas neighboring normally perfused regions reacted normally. Confinement of the regulation abnormalities to the area of the oligemia supports our suggestion that the blood flow changes are caused by a change in local metabolism. Between attacks of migraine, the patients had normal regulation of brain circulation.

AB - Cerebrovascular reactivity to voluntary hyperventilation, moderate hypertension, and physiological activation was studied in nine patients during induced migraine attacks and in four patients between their attacks. Regional cerebral blood flow was measured by the xenon 133 injection technique in 254 areas of one hemisphere. The partly hypoperfused hemisphere allowed for comparison of adjacent hypoperfused and normally perfused brain areas. During attacks the carbon dioxide reactivity was decreased to 2.8 ± 0.8% per mm Hg in the oligemic regions compared with 5.8 ± 0.8% per mm Hg in the normally perfused brain. Blood pressure autoregulation was normal in all brain regions. Regional blood flow increase in response to physiological activation was severely impaired in the hypoperfused brain areas, whereas neighboring normally perfused regions reacted normally. Confinement of the regulation abnormalities to the area of the oligemia supports our suggestion that the blood flow changes are caused by a change in local metabolism. Between attacks of migraine, the patients had normal regulation of brain circulation.

UR - http://www.scopus.com/inward/record.url?scp=0021032123&partnerID=8YFLogxK

U2 - 10.1002/ana.410140512

DO - 10.1002/ana.410140512

M3 - Journal article

C2 - 6418059

AN - SCOPUS:0021032123

VL - 14

SP - 569

EP - 572

JO - Annals of Neurology

JF - Annals of Neurology

SN - 0364-5134

IS - 5

ER -

ID: 201458958