Forskning ved Københavns Universitet - Københavns Universitet

Forside

Relative bioavailability in man of noscapine administered in lozenges and mixture

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

The bioavailability of noscapine base administered in lozenges in a dose of 100 mg to twelve healthy volunteers, in a study using an open balanced cross-over design, was compared with that of 100 mg of noscapine hydrochloride given perorally as a mixture. The bioavailability of noscapine after administration in lozenges was significantly higher than that after administration of the drug as a mixture. It is concluded that the lozenges containing noscapine base may be a valuable alternative to the conventional noscapine hydrochloride mixture.
OriginalsprogEngelsk
TidsskriftActa Pharmaceutica Nordica
Vol/bind4
Udgave nummer4
Sider (fra-til)309-312
Antal sider4
ISSN1100-1801
StatusUdgivet - 1 jan. 1992

ID: 46100967