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Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA)

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Neil R Poulter
  • Hans Wedel
  • Björn Dahlöf
  • Peter S Sever
  • D Gareth Beevers
  • Mark Caulfield
  • Sverre E Kjeldsen
  • Arni Kristinsson
  • Gordon T McInnes
  • Jesper Mehlsen
  • Markku Nieminen
  • Eoin O'Brien
  • Jan Ostergren
  • Stuart Pocock
  • ASCOT Investigators
Results of the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA) show significantly lower rates of coronary and stroke events in individuals allocated an amlodipine-based combination drug regimen than in those allocated an atenolol-based combination drug regimen (HR 0.86 and 0.77, respectively). Our aim was to assess to what extent these differences were due to significant differences in blood pressures and in other variables noted after randomisation.
OriginalsprogEngelsk
TidsskriftLancet
Vol/bind366
Udgave nummer9489
Sider (fra-til)907-13
Antal sider7
ISSN0140-6736
DOI
StatusUdgivet - sep. 2005

ID: 34079374