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Squamous cell carcinoma of the nasal vestibule 1993-2002: a nationwide retrospective study from DAHANCA

Publikation: Bidrag til tidsskriftTidsskriftartikel

  • Andreas Agger
  • Anders Rørbaek Madsen
  • Jesper Yde
  • Iana Lesnikova
  • Charlotte Birk Christensen
  • Søren Foghsgaard
  • Thomas Broe Christensen
  • Hanne Sand Hansen
  • Susanne Larsen
  • Jens Bentzen
  • Elo Andersen
  • Lisbeth Andersen
  • Cai Grau
  • Andreas Agger
  • Christian von Buchwald
  • Anders Rørbaek Madsen
  • Jesper Yde
  • Iana Lesnikova
  • Charlotte Christensen
  • Søren Foghsgaard
  • Thomas Broe Christensen
  • Hanne Sand Hansen
  • Susanne Larsen
  • Jens Dall Bentzen
  • Elo Andersen
  • Lisbeth Andersen
  • Cai Grau
BACKGROUND: A retrospective nationwide study of cancer of the nasal vestibule was conducted to evaluate classification systems and prognostic factors for treatment outcome. METHODS: Patients treated between 1993 and 2002 at head and neck oncology centers in Denmark were included. RESULTS: The 5-year results were locoregional control 67%, overall survival 50%, cancer-specific survival 74%. Cancer-specific survival according to Wang classification was 83%, 63%, and 39% for T1, T2, T3, respectively (p < .000). Regarding T1 tumors, 5-year locoregional control for surgery, surgery + radiotherapy (RT), or RT was 94%, 87%, or 61%, respectively (p < .000). Fifty-four Gray in 18 fractions was found comparable with 66 Gy in 33 fractions regarding T1 tumors. CONCLUSION: This national survey is the largest series of nasal vestibule cancer ever published. Wang classification is more prognostic and easier to use than the Union Internationale Contre le Cancer 2002. Surgery or hypofractionated RT can be used for T1 lesions, whereas larger lesions should be treated with combined approach
Udgivelsesdato: 2009/12
OriginalsprogEngelsk
TidsskriftHead & Neck (Print Edition)
Vol/bind31
Udgave nummer12
Sider (fra-til)1593-9
Antal sider7
ISSN1043-3074
DOI
StatusUdgivet - 1 dec. 2009

ID: 19663918