Forskning ved Københavns Universitet - Københavns Universitet

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Statistics and Informatics in Molecular Cancer Research

Publikation: Bog/antologi/afhandling/rapportBogForskningfagfællebedømt

This book discusses novel advances in informatics and statistics in molecular cancer research. Through eight chapters it discusses specific topics in cancer research, talks about how the topics give rise to development of new informatics and statistics tools, and explains how the tools can be applied. The focus of the book is to provide an understanding of key concepts and tools, rather than focusing on technical issues. A main theme is the extensive use of array technologies in modern cancer research - gene expression and exon arrays, SNP and copy number arrays and methylation arrays - to derive quantitative and qualitative statements about cancer, its progression and aetiology, and to understand how these technologies at one hand allow us learn about cancer tissue as a complex system and at the other hand allow us to pinpoint key genes and events as crucial for the development of the disease. Cancer is characterized by genetic and genomic alterations that influence all levels of the cell's machinery and function.

OriginalsprogEngelsk
ForlagOxford University Press
Vol/bind9780199532872
Antal sider208
ISBN (Trykt)9780199532872
ISBN (Elektronisk)9780191714467
DOI
StatusUdgivet - 1 sep. 2009
Eksternt udgivetJa

ID: 203906121