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Systemic treatment with epidermal growth factor in pigs induces ductal proliferations in the pancreas

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Epidermal growth factor (EGF), transforming growth factor alpha (TGF-alpha), and the EGF receptor are often overexpressed in chronic pancreatitis and in malignant pancreatic growth. Transgenic mice overexpressing TGF-alpha develop tissue changes in the pancrease resembling changes found in chronic pancreatitis. The effects of systemic treatment with EGF on the porcine pancrease were investigated in this study.
OriginalsprogEngelsk
TidsskriftGastroenterology
Vol/bind113
Udgave nummer4
Sider (fra-til)1367-1374
Antal sider8
ISSN0016-5085
StatusUdgivet - okt. 1997

ID: 226386