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Telomere length predicts all-cause mortality in patients with type 1 diabetes

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • A S Astrup
  • Lise Tarnow
  • A Jorsal
  • Marianne Lajer
  • R Nzietchueng
  • A Benetos
  • Pia Rossing
  • H-H Parving
Type 1 diabetic patients with diabetic nephropathy have increased mortality and morbidity compared with normoalbuminuric patients. Telomere length in proliferative cells is inversely related to the total number of cell divisions, and therefore to biological age. We aimed to evaluate differences in telomere length in patients with type 1 diabetes with or without diabetic nephropathy; we also evaluated the prognostic value of telomere length.
OriginalsprogEngelsk
TidsskriftDiabetologia
Vol/bind53
Udgave nummer1
Sider (fra-til)45-8
Antal sider4
ISSN0012-186X
DOI
StatusUdgivet - 1 jan. 2010

ID: 34163386