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The coalescent with gene conversion

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

In this article we develop a coalescent model with intralocus gene conversion. The distribution of the tract length is geometric in concordance with results published in the literature. We derive a simulation scheme and deduce a number of analytical results for this coalescent with gene conversion. We compare patterns of variability in samples simulated according to the coalescent with recombination with similar patterns simulated according to the coalescent with gene conversion alone. Further, an expression for the expected number of topology shifts in a sample of present- day sequences caused by gene conversion events is derived.

OriginalsprogEngelsk
TidsskriftGenetics
Vol/bind155
Udgave nummer1
Sider (fra-til)451-462
Antal sider12
ISSN0016-6731
StatusUdgivet - 1 maj 2000
Eksternt udgivetJa

ID: 203901560