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The epidermal growth factor precursor in the rat kidney seems to be processed by an aprotinin sensitive proteinase

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Epidermal growth factor (EGF) is synthesized as a membrane bound precursor in the rat kidney. The precursor seems to be processed by an aprotinin sensitive proteinase. Intravenous infusion of aprotinin reduces the urinary excretion of EGF by 85% and increases the amount of renal EGF. Kidney membranes incubated at 37 degrees C release EGF and this release is inhibited by aprotinin.
OriginalsprogEngelsk
TidsskriftAgents and actions. Supplements
Vol/bind38 ( Pt 2)
Sider (fra-til)183-90
Antal sider8
ISSN0379-0363
StatusUdgivet - 1992

ID: 47487685