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The expansion behaviour of sea anemones may be coordinated by two inhibitory neuropeptides, Antho-KAamide and Antho-RIamide

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Antho-KAamide (L-3-phenyllactyl-Phe-Lys-Ala-NH2) and Antho-RIamide (L-3-phenyllactyl-Tyr-Arg-Ile-NH2) are novel neuropeptides isolated from the sea anemone Anthopleura elegantissima. They both inhibited spontaneous contractions of isolated muscle preparations from a wide variety of anemone species (threshold around 10(-7) M). Their actions were universal in that they inhibited every muscle preparation tested, regardless of whether the muscle group was located in the ectoderm or endoderm, or was oriented in a circular or longitudinal direction. Injection of Antho-KAamide or Antho-RIamide into the coelenteron of intact sea anemones resulted in a marked expansion of the animals. Similar shape changes followed feeding or exposure to soluble food extracts. Therefore, we hypothesize that nerve cells that release Antho-KAamide and Antho-RIamide are involved in the expansion phase of feeding behaviour in sea anemones.
OriginalsprogEngelsk
TidsskriftRoyal Society of London. Proceedings. Biological Sciences
Vol/bind253
Udgave nummer1337
Sider (fra-til)183-8
Antal sider6
ISSN0962-8452
DOI
StatusUdgivet - 23 aug. 1993

ID: 33513941