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The genetic prehistory of the New World Arctic

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  • Maanasa Raghavan
  • Michael DeGiorgio
  • Pontus Skoglund
  • Bjarne Grønnow
  • Martin Appelt
  • Hans Christian Gulløv
  • T Max Friesen
  • William Fitzhugh
  • Helena Susanne Malmström
  • Jesper Olsen
  • Linea Cecilie Melchior
  • Benjamin T Fuller
  • Simon M Fahrni
  • Thomas Stafford jr.
  • Vaughan Grimes
  • M A Priscilla Renouf
  • Jerome Cybulski
  • Marta Mirazon Lahr
  • Kate Britton
  • Rick Knecht
  • Jette Arneborg
  • Mait Metspalu
  • Omar E Cornejo
  • Anna Sapfo Malaspinas
  • Yong Wang
  • Morten Rasmussen
  • Vibha Raghavan
  • Thomas van Overeem Hansen
  • Elza Khusnutdinova
  • Tracey Lynn Pierre
  • Kirill Dneprovsky
  • Claus Andreasen
  • Hans Lange
  • M Geoffrey Hayes
  • Joan Coltrain
  • Victor A Spitsyn
  • Anders Götherström
  • Ludovic Antoine Alexandre Orlando
  • Toomas Kivisild
  • Richard Villems
  • Michael H Crawford
  • Jørgen Dissing
  • Jan Heinemeier
  • Carlos Bustamante
  • Dennis H O'Rourke
  • Mattias Jakobsson
  • Rasmus Nielsen

The New World Arctic, the last region of the Americas to be populated by humans, has a relatively well-researched archaeology, but an understanding of its genetic history is lacking. We present genome-wide sequence data from ancient and present-day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia. We show that Paleo-Eskimos (~3000 BCE to 1300 CE) represent a migration pulse into the Americas independent of both Native American and Inuit expansions. Furthermore, the genetic continuity characterizing the Paleo-Eskimo period was interrupted by the arrival of a new population, representing the ancestors of present-day Inuit, with evidence of past gene flow between these lineages. Despite periodic abandonment of major Arctic regions, a single Paleo-Eskimo metapopulation likely survived in near-isolation for more than 4000 years, only to vanish around 700 years ago.

OriginalsprogEngelsk
TidsskriftScience
Vol/bind345
Udgave nummer6200
Antal sider9
ISSN0036-8075
DOI
StatusUdgivet - 2014

ID: 125945777