Forskning ved Københavns Universitet - Københavns Universitet

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The genome of the model beetle and pest Tribolium castaneum.

Publikation: Forskning - peer reviewTidsskriftartikel

Tribolium Genome Sequencing Consortium, Project leader, Stephen Richards, Principal investigators, Richard A Gibbs, George M Weinstock, White paper, Susan J Brown, Robin Denell, Richard W Beeman, Richard Gibbs, Analysis leaders, Richard W Beeman, Susan J Brown, Gregor Bucher, Markus Friedrich, Cornelis J P Grimmelikhuijzen, Martin Klingler, Marce Lorenzen, Stephen Richards & 244 andre Siegfried Roth, Reinhard Schröder, Diethard Tautz, Evgeny M Zdobnov, , Donna Muzny, Richard A Gibbs, George M Weinstock, Tony Attaway, Stephanie Bell, Christian J Buhay, Mimi N Chandrabose, Dean Chavez, Kerstin P Clerk-Blankenburg, Andrew Cree, Marvin Dao, Clay Davis, Joseph Chacko, Huyen Dinh, Shannon Dugan-Rocha, Gerald Fowler, Toni T Garner, Jeffrey Garnes, Andreas Gnirke, Alica Hawes, Judith Hernandez, Sandra Hines, Michael Holder, Jennifer Hume, Shalini N Jhangiani, Vandita Joshi, Ziad Mohid Khan, Laronda Jackson, Christie Kovar, Andrea Kowis, Sandra Lee, Lora R Lewis, Jon Margolis, Margaret Morgan, Lynne V Nazareth, Ngoc Nguyen, Geoffrey Okwuonu, David Parker, Stephen Richards, San-Juana Ruiz, Jireh Santibanez, Joël Savard, Steven E Scherer, Brian Schneider, Erica Sodergren, Diethard Tautz, Selina Vattahil, Donna Villasana, Courtney S White, Rita Wright, , Yoonseong Park, Richard W Beeman, Jeff Lord, Brenda Oppert, Marce Lorenzen, Susan Brown, Liangjiang Wang, Joël Savard, Diethard Tautz, Stephen Richards, George Weinstock, Richard A Gibbs, , Yue Liu, Kim Worley, George Weinstock, , Christine G Elsik, Justin T Reese, Eran Elhaik, Giddy Landan, Dan Graur, , Peter Arensburger, Peter Atkinson, Richard W Beeman, Jim Beidler, Susan J Brown, Jeffery P Demuth, Douglas W Drury, Yu-Zhou Du, Haruhiko Fujiwara, Marce Lorenzen, Vincenza Maselli, Mizuko Osanai, Yoonseong Park, Hugh M Robertson, Zhijian Tu, Jian-Jun Wang, Suzhi Wang, , Stephen Richards, Henry Song, Lan Zhang, Erica Sodergren, Doreen Werner, Mario Stanke, Burkhard Morgenstern, Victor Solovyev, Peter Kosarev, Garth Brown, Hsiu-Chuan Chen, Olga Ermolaeva, Wratko Hlavina, Yuri Kapustin, Boris Kiryutin, Paul Kitts, Donna Maglott, Kim Pruitt, Victor Sapojnikov, Alexandre Souvorov, Aaron J Mackey, Robert M Waterhouse, Stefan Wyder, Evgeny M Zdobnov, , Evgeny M Zdobnov, Stefan Wyder, Evgenia V Kriventseva, Tatsuhiko Kadowaki, Peer Bork, , Manuel Aranda, Riyue Bao, Anke Beermann, Nicola Berns, Renata Bolognesi, François Bonneton, Daniel Bopp, Susan J Brown, Gregor Bucher, Thomas Butts, Arnaud Chaumot, Robin E Denell, David E K Ferrier, Markus Friedrich, Cassondra M Gordon, Marek Jindra, Martin Klingler, Que Lan, H Michael G Lattorff, Vincent Laudet, Cornelia von Levetsow, Zhenyi Liu, Rebekka Lutz, Jeremy A Lynch, Rodrigo Nunes da Fonseca, Nico Posnien, Rolf Reuter, Siegfried Roth, Joël Savard, Johannes B Schinko, Christian Schmitt, Michael Schoppmeier, Reinhard Schröder, Teresa D Shippy, Franck Simonnet, Henrique Marques-Souza, Diethard Tautz, Yoshinori Tomoyasu, Jochen Trauner, Maurijn Van der Zee, Michel Vervoort, Nadine Wittkopp, Ernst A Wimmer, Xiaoyun Yang, , Andrew K Jones, David B Sattelle, , Paul R Ebert, , David Nelson, Jeffrey G Scott, Richard W Beeman, , Subbaratnam Muthukrishnan, Karl J Kramer, Yasuyuki Arakane, Richard W Beeman, Qingsong Zhu, David Hogenkamp, Radhika Dixit, , Brenda Oppert, Haobo Jiang, Zhen Zou, Jeremy Marshall, Elena Elpidina, Konstantin Vinokurov, Cris Oppert, , Zhen Zou, Jay Evans, Zhiqiang Lu, Picheng Zhao, Niranji Sumathipala, Boran Altincicek, Andreas Vilcinskas, Michael Williams, Dan Hultmark, Charles Hetru, Haobo Jiang, , Cornelis J P Grimmelikhuijzen, Frank Hauser, Giuseppe Cazzamali, Michael Williamson, Yoonseong Park, Bin Li, Yoshiaki Tanaka, Reinhard Predel, Susanne Neupert, Joachim Schachtner, Peter Verleyen, , Florian Raible, Peer Bork, , Markus Friedrich, , Kimberly K O Walden, Hugh M Robertson, , Sergio Angeli, Sylvain Forêt, Gregor Bucher, Stefan Schuetz, Ryszard Maleszka, Ernst A Wimmer, , Richard W Beeman, Marce Lorenzen, , Yoshinori Tomoyasu, Sherry C Miller, Daniela Grossmann, Gregor Bucher

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more representative of other insects than is Drosophila, a fact reflected in gene content and function. For example, Tribolium has retained more ancestral genes involved in cell-cell communication than Drosophila, some being expressed in the growth zone crucial for axial elongation in short-germ development. Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control.
Udgivelsesdato: e-pub.2008-Apr-24
OriginalsprogEngelsk
TidsskriftNature
Vol/bind452
Tidsskriftsnummer7190
Sider (fra-til)949-955
Antal sider7
ISSN0028-0836
DOI
StatusUdgivet - 2008

ID: 3337610