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Two lectin-like receptors for alpha 1-acid glycoprotein in mouse testis

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Standard

Two lectin-like receptors for alpha 1-acid glycoprotein in mouse testis. / Andersen, U O; Kirkeby, S; Bøg-Hansen, T C.

I: Journal of Molecular Recognition, Bind 9, Nr. 5-6, 1997, s. 364-7.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Andersen, UO, Kirkeby, S & Bøg-Hansen, TC 1997, 'Two lectin-like receptors for alpha 1-acid glycoprotein in mouse testis', Journal of Molecular Recognition, bind 9, nr. 5-6, s. 364-7. https://doi.org/10.1002/(SICI)1099-1352(199634/12)9:5/6<364::AID-JMR266>3.0.CO;2-6

APA

Andersen, U. O., Kirkeby, S., & Bøg-Hansen, T. C. (1997). Two lectin-like receptors for alpha 1-acid glycoprotein in mouse testis. Journal of Molecular Recognition, 9(5-6), 364-7. https://doi.org/10.1002/(SICI)1099-1352(199634/12)9:5/6<364::AID-JMR266>3.0.CO;2-6

Vancouver

Andersen UO, Kirkeby S, Bøg-Hansen TC. Two lectin-like receptors for alpha 1-acid glycoprotein in mouse testis. Journal of Molecular Recognition. 1997;9(5-6):364-7. https://doi.org/10.1002/(SICI)1099-1352(199634/12)9:5/6<364::AID-JMR266>3.0.CO;2-6

Author

Andersen, U O ; Kirkeby, S ; Bøg-Hansen, T C. / Two lectin-like receptors for alpha 1-acid glycoprotein in mouse testis. I: Journal of Molecular Recognition. 1997 ; Bind 9, Nr. 5-6. s. 364-7.

Bibtex

@article{b8b226e0f1e911ddbf70000ea68e967b,
title = "Two lectin-like receptors for alpha 1-acid glycoprotein in mouse testis",
abstract = "Three glycoforms of alpha 1-acid glycoprotein (AGP) were biotinylated to examine their binding in mouse testis by light microscopy. The transition from one stage to another in the spermatogenic cycle is marked with an appearance of a receptor for the Concanavalin A (Con A) non-reactive glycoform AGP-A in the cytoplasm of spermatocytes, young spermatids and Sertoli cells. This receptor disappears in the late stages of the spermatids. The Con-A intermediately reactive and the Con-A reactive glycoforms, AGP-B and AGP-C, showed weak reaction in the cytoplasm of spermatocytes, spermatids and Sertoli cells and, at the last stages in the spermatogenic cycle, a very strong reaction in the late elongated spermatids and the apical extensions of Sertoli cells. The interactions are lectin-like as confirmed by inhibition with simple sugars. In addition, the bindings were inhibited by steroid hormones. AGP-A was inhibited by testosterone, oestradiol and progesterone, while AGP-B and AGP-C were inhibited by mannose, GlcNAc, cortisone, aldosterone, oestradiol and progesterone. The receptors and the corresponding AGP glycoforms may be adhesion molecules between Sertoli cells and the spermatogenic cells and may have a function as a regulatory factor for spermatozoa development.",
author = "Andersen, {U O} and S Kirkeby and B{\o}g-Hansen, {T C}",
note = "Keywords: Animals; Humans; Lectins; Male; Mice; Orosomucoid; Receptors, Cell Surface; Testis",
year = "1997",
doi = "10.1002/(SICI)1099-1352(199634/12)9:5/6<364::AID-JMR266>3.0.CO;2-6",
language = "English",
volume = "9",
pages = "364--7",
journal = "Journal of Molecular Recognition",
issn = "0952-3499",
publisher = "Wiley",
number = "5-6",

}

RIS

TY - JOUR

T1 - Two lectin-like receptors for alpha 1-acid glycoprotein in mouse testis

AU - Andersen, U O

AU - Kirkeby, S

AU - Bøg-Hansen, T C

N1 - Keywords: Animals; Humans; Lectins; Male; Mice; Orosomucoid; Receptors, Cell Surface; Testis

PY - 1997

Y1 - 1997

N2 - Three glycoforms of alpha 1-acid glycoprotein (AGP) were biotinylated to examine their binding in mouse testis by light microscopy. The transition from one stage to another in the spermatogenic cycle is marked with an appearance of a receptor for the Concanavalin A (Con A) non-reactive glycoform AGP-A in the cytoplasm of spermatocytes, young spermatids and Sertoli cells. This receptor disappears in the late stages of the spermatids. The Con-A intermediately reactive and the Con-A reactive glycoforms, AGP-B and AGP-C, showed weak reaction in the cytoplasm of spermatocytes, spermatids and Sertoli cells and, at the last stages in the spermatogenic cycle, a very strong reaction in the late elongated spermatids and the apical extensions of Sertoli cells. The interactions are lectin-like as confirmed by inhibition with simple sugars. In addition, the bindings were inhibited by steroid hormones. AGP-A was inhibited by testosterone, oestradiol and progesterone, while AGP-B and AGP-C were inhibited by mannose, GlcNAc, cortisone, aldosterone, oestradiol and progesterone. The receptors and the corresponding AGP glycoforms may be adhesion molecules between Sertoli cells and the spermatogenic cells and may have a function as a regulatory factor for spermatozoa development.

AB - Three glycoforms of alpha 1-acid glycoprotein (AGP) were biotinylated to examine their binding in mouse testis by light microscopy. The transition from one stage to another in the spermatogenic cycle is marked with an appearance of a receptor for the Concanavalin A (Con A) non-reactive glycoform AGP-A in the cytoplasm of spermatocytes, young spermatids and Sertoli cells. This receptor disappears in the late stages of the spermatids. The Con-A intermediately reactive and the Con-A reactive glycoforms, AGP-B and AGP-C, showed weak reaction in the cytoplasm of spermatocytes, spermatids and Sertoli cells and, at the last stages in the spermatogenic cycle, a very strong reaction in the late elongated spermatids and the apical extensions of Sertoli cells. The interactions are lectin-like as confirmed by inhibition with simple sugars. In addition, the bindings were inhibited by steroid hormones. AGP-A was inhibited by testosterone, oestradiol and progesterone, while AGP-B and AGP-C were inhibited by mannose, GlcNAc, cortisone, aldosterone, oestradiol and progesterone. The receptors and the corresponding AGP glycoforms may be adhesion molecules between Sertoli cells and the spermatogenic cells and may have a function as a regulatory factor for spermatozoa development.

U2 - 10.1002/(SICI)1099-1352(199634/12)9:5/6<364::AID-JMR266>3.0.CO;2-6

DO - 10.1002/(SICI)1099-1352(199634/12)9:5/6<364::AID-JMR266>3.0.CO;2-6

M3 - Journal article

C2 - 9174911

VL - 9

SP - 364

EP - 367

JO - Journal of Molecular Recognition

JF - Journal of Molecular Recognition

SN - 0952-3499

IS - 5-6

ER -

ID: 10116313