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Unicortical critical size defect of rabbit tibia is larger than 8 mm

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  • M Aaboe
  • E M Pinholt
  • E Hjørting-Hansen
The critical-size defect is important as an experimental model to test bone repair materials. Guided tissue regeneration is an established method for tissue regeneration within periodontal surgery. Bony defects covered by a membrane are allowed to be filled by bony tissue. Healing of 8-mm unicortical trephine defects was tested in Copenhagen White rabbit tibia using 3 different membranes. The critical-size defect in Copenhagen White rabbit tibia is larger than 8 mm, because control defects 8 mm in diameter healed spontaneously. However, it is anatomically not possible to create defects larger than 8 mm in an adult Copenhagen White rabbit tibia.
OriginalsprogEngelsk
TidsskriftJournal of Craniofacial Surgery
Vol/bind5
Udgave nummer3
Sider (fra-til)201-3
Antal sider3
ISSN1049-2275
StatusUdgivet - 1 jul. 1994

ID: 33984565