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USING OXYGEN-CONSUMING THERMOSET PLASTICS TO GENERATE HYPOXIC CONDITIONS IN MICROFLUIDIC DEVICES FOR POTENTIAL CELL CULTURE APPLICATIONS

Publikation: KonferencebidragKonferenceabstrakt til konferenceForskningfagfællebedømt

Dokumenter

The precise control of the oxygen concentration in a cellular environment allows the study of cells under physiologically relevant conditions. This work reports on a novel method for the generation of reduced dissolved oxygen concentrations in microfluidic chambers for cell- and organ-on-chip applications. Using a thermoset polymeric material (OSTEMERTM), which effectively scavenges dissolved oxygen (DO), microfluidic devices have been fabricated where oxygen was rapidly depleted from the microfluidic chamber. It is shown that hypoxic and anaerobic conditions can be generated through the inherent scavenging property of the material itself, without any additional chemical additives.
OriginalsprogEngelsk
Publikationsdatookt. 2017
Antal sider2
StatusUdgivet - okt. 2017
BegivenhedThe 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017) - Savannah, Georgia, USA, Savannah, USA
Varighed: 22 okt. 201726 okt. 2017

Konference

KonferenceThe 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017)
LokationSavannah, Georgia, USA
LandUSA
BySavannah
Periode22/10/201726/10/2017

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