Forskning ved Københavns Universitet - Københavns Universitet

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Albert Jelke Kooistra
Albert Jelke Kooistra

Assistant professor


  1. 2021
  2. Published

    GPCR activation mechanisms across classes and macro/microscales

    Hauser, Alexander Sebastian, Kooistra, Albert Jelke, Munk, C., Heydenreich, F. M., Veprintsev, D. B., Bouvier, M., Babu, M. M. & Gloriam, David E., 2021, In: Nature Structural and Molecular Biology. 28, 11, p. 879-888

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    KLIFS: an overhaul after the first 5 years of supporting kinase research

    Kanev, G. K., de Graaf, C., Westerman, B. A., de Esch, I. J. P. & Kooistra, Albert Jelke, 2021, In: Nucleic Acids Research. 49, D1, p. D562-D569

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    GPCRdb in 2021: integrating GPCR sequence, structure and function

    Kooistra, Albert Jelke, Mordalski, S., Pándy-Szekeres, G., Esguerra, M., Mamyrbekov, Alibek, Munk, C., Keserű, G. M. & Gloriam, David E., 2021, In: Nucleic Acids Research. 49, D1, p. D335-D343

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    An online GPCR structure analysis platform

    Kooistra, Albert Jelke, Munk, C., Hauser, Alexander Sebastian & Gloriam, David E., 2021, In: Nature Structural and Molecular Biology. 28, 11, p. 875-878

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Structure of the class D GPCR Ste2 dimer coupled to two G proteins

    Velazhahan, V., Ma, N., Pandy-Szekeres, G., Kooistra, Albert Jelke, Lee, Y., Gloriam, David E., Vaidehi, N. & Tate, C. G., 2021, In: Nature. 589, p. 148-153 +app 24 pp

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Discovery of Diaryl Ether Substituted Tetrahydrophthalazinones as TbrPDEB1 Inhibitors Following Structure-Based Virtual Screening

    de Heuvel, E., Kooistra, Albert Jelke, Edink, E., van Klaveren, S., Stuijt, J., van der Meer, T., Sadek, P., Mabille, D., Caljon, G., Maes, L., Siderius, M., de Esch, I. J. P., Sterk, G. J. & Leurs, R., 21 Jan 2021, In: Frontiers in Chemistry. 8, 10 p., 608030.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2020
  9. Published

    Utilizing drug-target-event relationships to unveil safety patterns in pharmacovigilance

    Hauser, Alexander Sebastian, Kooistra, Albert Jelke, Sverrisdóttir, Eva & Sessa, Maurizio, 2020, In: Expert Opinion on Drug Safety. 19, p. 961-968

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists

    Zhang, X., Belousoff, M. J., Zhao, P., Kooistra, Albert Jelke, Truong, T. T., Ang, S. Y., Underwood, C. R., Egebjerg, T., Šenel, P., Stewart, G. D., Liang, Y., Glukhova, A., Venugopal, H., Christopoulos, A., Furness, S. G. B., Miller, L. J., Reedtz-Runge, S., Langmead, C. J., Gloriam, David E., Danev, R., Sexton, P. M. & Wootten, D., 2020, In: Molecular Cell. 80, 3, p. 485-500

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2019
  12. Route to Prolonged Residence Time at the Histamine H1 Receptor: Growing from Desloratadine to Rupatadine

    Bosma, R., Wang, Z., Kooistra, Albert Jelke, Bushby, N., Kuhne, S., van den Bor, J., Waring, M. J., de Graaf, C., de Esch, I. J., Vischer, H. F., Sheppard, R. J., Wijtmans, M. & Leurs, R., 25 Jul 2019, In: Journal of Medicinal Chemistry. 62, 14, p. 6630-6644 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. The Landscape of Atypical and Eukaryotic Protein Kinases

    Kanev, G. K., de Graaf, C., de Esch, I. J. P., Leurs, R., Würdinger, T., Westerman, B. A. & Kooistra, Albert Jelke, Nov 2019, In: Trends in Pharmacological Sciences. 40, 11, p. 818-832 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

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