Forskning ved Københavns Universitet - Københavns Universitet

Forside
Albert Jelke Kooistra
Albert Jelke Kooistra

Assistant professor


  1. 2015
  2. Analyzing multitarget activity landscapes using protein-ligand interaction fingerprints: Interaction cliffs

    Méndez-Lucio, O., Kooistra, Albert Jelke, Graaf, C. D., Bender, A. & Medina-Franco, J. L., 23 Feb 2015, In: Journal of Chemical Information and Modeling. 55, 2, p. 251-262 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2014
  4. KLIFS: A knowledge-based structural database to navigate kinase-ligand interaction space

    Van Linden, O. P. J., Kooistra, Albert Jelke, Leurs, R., De Esch, I. J. P. & De Graaf, C., 23 Jan 2014, In: Journal of Medicinal Chemistry. 57, 2, p. 249-277 29 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. From three-dimensional GPCR structure to rational ligand discovery

    Kooistra, Albert Jelke, Leurs, R., De Esch, I. J. P. & Graaf, C. D., 1 Jan 2014, G Protein-Coupled Receptors - Modeling and Simulation. Springer New York LLC, p. 129-157 29 p. (Advances in Experimental Medicine and Biology, Vol. 796).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  6. The Receptor Concept in 3D: From Hypothesis and Metaphor to GPCR–Ligand Structures

    Kooistra, Albert Jelke, de Graaf, C. & Timmerman, H., 1 Jan 2014, In: Neurochemical Research. 39, 10, p. 1850-1861 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. 2013
  8. A structural chemogenomics analysis of aminergic GPCRs: Lessons for histamine receptor ligand design

    Kooistra, Albert Jelke, Kuhne, S., De Esch, I. J. P., Leurs, R. & De Graaf, C., 1 Sep 2013, In: British Journal of Pharmacology. 170, 1, p. 101-126 26 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Small and colorful stones make beautiful mosaics: Fragment-based chemogenomics

    De Graaf, C., Vischer, H. F., De Kloe, G. E., Kooistra, Albert Jelke, Nijmeijer, S., Kuijer, M., Verheij, M. H. P., England, P. J., Van Muijlwijk-Koezen, J. E., Leurs, R. & De Esch, I. J. P., 1 Apr 2013, In: Drug Discovery Today. 18, 7-8, p. 323-330 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Discovery of novel Trypanosoma brucei phosphodiesterase B1 inhibitors by virtual screening against the unliganded TbrPDEB1 crystal structure

    Jansen, C., Wang, H., Kooistra, Albert Jelke, De Graaf, C., Orrling, K. M., Tenor, H., Seebeck, T., Bailey, D., De Esch, I. J. P., Ke, H. & Leurs, R., 14 Mar 2013, In: Journal of Medicinal Chemistry. 56, 5, p. 2087-2096 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. From heptahelical bundle to hits from the haystack: Structure-based virtual screening for GPCR ligands

    Kooistra, Albert Jelke, Roumen, L., Leurs, R., De Esch, I. J. P. & De Graaf, C., 11 Feb 2013, G Protein Coupled ReceptorsModeling, Activation, Interactions and Virtual Screening. p. 279-336 58 p. (Methods in Enzymology, Vol. 522).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  12. Mapping histamine H4 receptor-ligand binding modes

    Schultes, S., Nijmeijer, S., Engelhardt, H., Kooistra, Albert Jelke, Vischer, H. F., De Esch, I. J. P., Haaksma, E. E. J., Leurs, R. & De Graaf, C., 1 Jan 2013, In: MedChemComm. 4, 1, p. 193-204 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2012
  14. Virtual fragment screening: Discovery of histamine H3 receptor ligands using ligand-based and protein-based molecular fingerprints

    Sirci, F., Istyastono, E. P., Istyastono, E. P., Vischer, H. F., Kooistra, Albert Jelke, Nijmeijer, S., Kuijer, M., Wijtmans, M., Mannhold, R., Leurs, R., De Esch, I. J. P. & De Graaf, C., 21 Dec 2012, In: Journal of Chemical Information and Modeling. 52, 12, p. 3308-3324 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 196033213