Forskning ved Københavns Universitet - Københavns Universitet

Forside
Jens Bukh
Jens Bukh

Professor

  • Virology

    Blegdamsvej 3B, 07 Bygning 7, Building: 07-13-84

    2200 København N

    Mobile: +4523418969

  1. 2019
  2. Published

    Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis c virus infections uncover molecular determinants for E2 targeting and vaccine design

    Keck, Z. Y., Pierce, B. G., Lau, P., Lu, J., Wang, Y., Underwood, A., Bull, R. A., Prentø, Jannick, Velázquez-Moctezuma, R., Walker, Melanie Rose, Luciani, F., Guest, J. D., Fauvelle, C., Baumert, T. F., Bukh, Jens, Lloyd, A. R. & Foung, S. K. H., 2019, In: P L o S Pathogens. 15, 5, 28 p., e1007772.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Evolutionary Pathways to Persistence of Highly Fit and Resistant Hepatitis C Virus Protease Inhibitor Escape Variants

    Jensen, S. B., Fahnøe, Ulrik, Pham, Long, Serre, S. B. N., Tang, Q., Ghanem, L., Pedersen, M. S., Ramirez Almeida, Santseharay, Humes, D., Pihl, A. F., Filskov, J., Sølund, C. S., Dietz, J., Fourati, S., Pawlotsky, J. M., Sarrazin, C., Weis, Nina, Schønning, Kristian, Krarup, H., Bukh, Jens & Gottwein, Judith Margarete, 2019, In: Hepatology. 70, 3, p. 771-787 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Full-length open reading frame amplification of hepatitis C virus

    Fahnøe, Ulrik & Bukh, Jens, 2019, Hepatitis C Virus Protocols. Humana Press, p. 85-91 7 p. (Methods in Molecular Biology, Vol. 1911).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  5. Published

    Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies

    Tzarum, N., Giang, E., Kong, L., He, L., Prentø, Jannick, Augestad, E., Hua, Y., Castillo, S., Lauer, G. M., Bukh, Jens, Zhu, J., Wilson, I. A. & Law, M., 2019, In: Science Advances. 5, 1, 12 p., eaav1882.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Genome sequence of an unknown subtype of hepatitis C virus genotype 6: Another piece for the taxonomic puzzle

    Pedersen, M. S., Mollerup, S., Nielsen, L. G., Jenssen, H., Bukh, Jens & Schønning, Kristian, 2019, In: Microbiology resource announcements. 8, 42, e01030-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    HCV genotype 1-6 NS3 residue 80 substitutions impact protease inhibitor activity and promote viral escape

    Pham, Long, Jensen, S. B., Fahnøe, Ulrik, Pedersen, M. S., Tang, Q., Ghanem, L., Ramirez Almeida, Santseharay, Humes, D., Serre, S. B. N., Schønning, Kristian, Bukh, Jens & Gottwein, Judith Margarete, 2019, In: Journal of Hepatology. 70, 3, p. 388-397

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    HCV p7 as a novel vaccine-target inducing multifunctional CD4+ and CD8+ T-cells targeting liver cells expressing the viral antigen

    Filskov, J., Andersen, P., Agger, E. M. & Bukh, Jens, 2019, In: Scientific Reports. 9, 1, 13 p., 14085.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Hepatitis C Virus–Escape Studies for Human Monoclonal Antibody AR4A Reveal Isolate-Specific Resistance and a High Barrier to Resistance

    Velázquez-moctezuma, R., Galli, Andrea, Law, M., Bukh, Jens & Prentø, Jannick, 2019, In: The Journal of Infectious Diseases. 219, 1, p. 68-79

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Hepatitis C virus escape studies of human antibody AR3a reveal a high barrier to resistance and novel insights on viral antibody evasion mechanisms

    Velázquez-Moctezuma, R., Galli, Andrea, Law, M., Bukh, Jens & Prentø, Jannick, 2019, In: Journal of Virology. 93, 4, 27 p., e0190918.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Hypervariable region 1 and N-linked glycans of hepatitis C regulate virion neutralization by modulating envelope conformations

    Prentø, Jannick, Velázquez-Moctezuma, R., Augestad, E. H., Galli, Andrea, Wang, R., Law, M., Alter, H. & Bukh, Jens, 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 20, p. 10039-10047 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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