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Efficacy of 10-20-30 training versus moderate-intensity continuous training on HbA1c, body composition and maximum oxygen uptake in male patients with type 2 diabetes: A randomized controlled trial

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Aim: To compare the efficacy of 10-20-30 training versus moderate-intensity continuous training (MICT) on HbA1c, body composition and maximum oxygen uptake (V˙O2max) in male patients with type 2 diabetes (T2D).

Materials and Methods: Fifty-one male participants with T2D were randomly assigned (1:1) to a 10-20-30 (N = 26) and a MICT (N = 25) training group. Interventions consisted of supervised cycling three times weekly for 10 weeks, lasting 29 minutes (10-20-30) and 50 minutes (MICT) in a local non-clinical setting. The primary outcome was change in HbA1c from baseline to 10-week follow-up.

Results: Of 51 participants enrolled, 44 (mean age 61.0 ± 6.8 [mean ± SD] years, diagnosed 7.5 ± 5.8 years, baseline HbA1c 7.4% ± 1.3%) were included in the analysis. Training compliance was 84% and 86% in 10-20-30 and MICT, respectively. No adverse events occurred during the intervention. HbA1c decreased (P  <0.001) by 0.5 (95% CI -0.72 to -0.21) percentage points with training in 10-20-30, with no change in MICT. The change in 10-20-30 was greater (P  <0.05) than in MICT. Visceral fat mass decreased (P  <0.05) only with 10-20-30 training, whereas total fat mass decreased (P  <0.01) and V˙O2max increased (P  <0.01) with training in both groups.

Conclusions: Ten weeks of 10-20-30 training was superior to MICT in lowering HbA1c, and only 10-20-30 training decreased visceral fat mass in patients with T2D. Furthermore, 10-20-30 training was as effective as MICT in reducing total fat mass and increasing V˙O2max, despite a 42% lower training time commitment.

Original languageEnglish
JournalDiabetes, Obesity and Metabolism
Volume22
Issue number5
Pages (from-to)767-778
Number of pages12
ISSN1462-8902
DOIs
Publication statusPublished - 2020

Bibliographical note

© 2020 John Wiley & Sons Ltd.

    Research areas

  • Faculty of Science - Glycaemic control, High-intensity interval training, Oral glucose tolerance test, Skeletal muscle protein adaptations, Sprint-interval training

ID: 237471514